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Evidence Synthesis: Research Question, Framework, Conducting and Reporting Methodology: List of Question Examples and Review Methodology

List the question framework for different types; for the question framework for a systematic review is PICO.

Review Type and Example Question

1) Systematic Review

Question: Are chlorhexidine (CHG) dressings effective and safe to reduce catheter-related bloodstream infections (CRBI)?

Puig-Asensio M, Marra AR, Childs CA, Kukla ME, Perencevich EN, Schweizer ML. Effectiveness of chlorhexidine dressings to prevent catheter-related bloodstream infections. Does one size fit all? A systematic literature review and meta-analysis. Infect Control Hosp Epidemiol. 2020 Sep 16:1-8.             doi: 10.1017/ice.2020.356      PMID: 32935659

 

2) Qualitative Review

Example Question from a Study: How do patients diagnosed with COVID-19 feel about their experience in the pandemic of COVID-19?

Zheng X, Qian M, Ye X, Zhang M, Zhan C, Li H, Luo T. Implications for long COVID: A systematic review and meta-aggregation of experience of patients diagnosed with COVID-19. J Clin Nurs. 2022 Oct 17:10.1111/jocn.16537. doi: 10.1111/jocn.16537. Epub ahead of print. PMID: 36253950; PMCID: PMC9874539.

 

3) Comparative Effectiveness

Questions from an Example Study

• Whether the effectiveness of different non-pharmacological interventions on reducing ICU delirium are different?

• Which non-pharmacological intervention is the most effective for preventing delirium in critically ill ICU patients?

Chen TJ, Traynor V, Wang AY, Shih CY, Tu MC, Chuang CH, Chiu HY, Chang HR. Comparative effectiveness of non-pharmacological interventions for preventing delirium in critically ill adults: A systematic review and network meta-analysis. Int J Nurs Stud. 2022 Jul;131:104239.

doi: 10.1016/j.ijnurstu.2022.104239        Epub 2022 Mar 28.     PMID: 35468538.

 

4) Systematic Reviews of Text and Opinion

Example Question from a Study

What are the experiences of health professionals working with adults who have survived into old age, and who are now experiencing problems or eliciting behaviour related to the past trauma of childhood sexual abuse?

Dodd, M., & George, C. (2011). Health professionals’ experiences with older adults affected by the trauma of their childhood sexual abuse: a systematic review of text and expert opinion. JBI Library of Systematic Reviews, 9, 1–21. https://doi.org/10.11124/jbisrir-2011-313

 

5) Systematic Reviews of Prevalence and Incidence

Example Questions from a Study

1) What is the effect on (self)-repositioning ability during a 12-week period in which nursing home residents at risk of PUs are cared for on subsequently a cotton mattress sheet (first 6 weeks) and a breathable silk-like, 3-layer ventilating mattress sheet (second 6 weeks)?

2) What is the pressure ulcer incidence during a 12-week period when nursing home residents at risk of PUs are cared for on subsequently a cotton mattress sheet (first 6 weeks) and a breathable silk-like, 3-layer ventilating mattress sheet (second 6 weeks)?

van Leen, M. W. F., van Ratingen, W. I. J., & Schols, J. M. G. A. (2022). Effects of a breathable silk-like, 3-layer ventilating mattress sheet on self- repositioning, repositioning support and pressure ulcer incidence; a pragmatic observational study. Wounds International, 13(1), 38–45.

           http://ezproxy.ttuhsc.edu/loginurl=https://search.ebscohost.com/login.aspxdirect=true&db=ccm&AN=155735897&site=ehost-live

 

6)  Systematic reviews of economic evidence

Article Examples

de Verteuil R. & Shin T.W. (2010) Self-monitoring of blood glucose in type 2 diabetes mellitus: a systematic review of economic evidence. JBI Library of Systematic Reviews 8(7), 302–342. JBL000241.

Access from: 1)  Go to  https://ttuhsc.libguides.com and on the left side of the screen, click journals and search JBI Library of Systematic Reviews.  On the next screen click Journals at Ovid.  Scroll to Journal Issue List on the left side of the screen.  Open the year 2010.  Locate and click  Vol. 8(7).

OR from:      2)   https://www.researchgate.net/publication/333841535_Self             monitoring_of_blood_glucose_in_type_2_diabetes_mellitus_systematic_review_of_economic_evidence

            See also:   LOCKWOOD C. (2010) Review Summaries: de Verteuil R. & Shin T.W. (2010) Self-monitoring of blood glucose in type 2 diabetes mellitus: a systematic review of economic evidence. Journal of Advanced Nursing 66(9), 1931–1936.   https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2648.2010.5414.x

 

7) Systematic Review of Etiology/Risk/Benefit

Question: What are the risk factors associated with hospital readmission within seven, 15, 30, 60, 90, 180, and 365 days of discharge among patients 18 years or older with HFrEF (LVEF < 40%).

Schjødt I, Liljeroos M, Larsen P, Johnsen SP, Strömberg A, Løgstrup BB. Risk factors for hospital readmission in adult patients with heart failure with reduced ejection fraction: a systematic review. JBI Evid Synth. 2020 Aug; 18(8):1641-1700. doi: 10.11124/JBISRIR-D-19-00203. PMID: 32898362

 

8) Mixed Methods

Questions: In this review we focused on the pertinent issues specifically related to medication management for individuals living at home and receiving homecare services and were guided by the following research questions:

1. What are the issues encountered by individuals, families, caregivers and healthcare providers related to the medication management of individuals living in the community and receiving homecare services?

2. What are the documented errors or adverse events that occur in this population that relate to the management of their medications?

3. What strategies have been implemented and evaluated in the home setting that address the issues related to medication management encountered by this population?

Godfrey, C. M. , Harrison, M. B. , Lang, A. , Macdonald, M. , Leung, T. & Swab, M. (2013). JBI Database of Systematic Reviews and Implementation Reports, 11 (7), 82-130.       doi: 10.11124/jbisrir-2013-959.        

https://journals.lww.com/jbisrir/Fulltext/2013/11070/Homecare_safety_and_medication_management_with.3.aspx

https://oce.ovid.com/article/01938924-201311070-00003/PDF

 

9)  Diagnostic Test Accuracy

Question/Objective: “To determine the diagnostic accuracy of currently available laboratory tests for swine flu (H1N1) using viral culture as a reference test amongst people presenting with suspected flu” which could alternatively be phrased as the question “What is the diagnostic accuracy of currently available laboratory tests for swine flu (H1N1) compared to viral culture as a reference test amongst people presenting with suspected flu?”

Delgado K, Williams M. Diagnostic accuracy for coronary artery disease of multislice CT scanners in comparison to conventional coronary angiography: an integrative literature review. J Am Acad Nurse Pract. 2010 Sep;22(9):496-503.

DOI: 10.1111/j.1745-7599.2010.00501.x      PMID: 20854642        https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1745-7599.2010.00501.x

 

10)  Umbrella Review

Question:  What are the differences between the ultrasound-guided versus traditional method for venous and arterial access in adult and pediatric population? 

Berlanga-Macías, C., Díez-Fernández, A., Martínez-Hortelano, J.A. et al. Ultrasound-guided versus traditional method for peripheral venous access: an umbrella review. BMC Nurs 21, 307 (2022).  doi: 10.1186/s12912-022-01077-9

 

11)  Scoping review

Questions

What fasting times are implemented prior to general anesthesia among adult intubated ICU patients?

Do fasting times vary depending on the type of surgical intervention?

What outcomes, including but not limited to aspiration, malnutrition, and mortality, have been reported following the cessation of EN prior to general anesthesia among adult intubated ICU patients?

Barrick CG, Stewart MW, Palokas M. Enteral nutrition for intubated adults in the intensive care unit prior to general anesthesia: a scoping review. JBI Evid Synth. 2020 Aug;18(8):1701-1723.           

doi: 10.11124/JBISRIR-D-19-00123             PMID: 32898363

 

12) Systematic reviews of measurement properties

Question/Objective

The objective of this review was to evaluate the measurement properties (reliability, validity, and responsiveness) of the multidimensional pain assessment tools that are used to assess postoperative pain in adults.

Lapkin, S., Elwood, L., Diwan, A., & Fernandez, R. (2021). Reliability, validity, and responsiveness of multidimensional pain assessment tools used in postoperative adult patients: a systematic review of measurement properties. JBI Evidence Synthesis, 19(2), 284-307. 

DOI: 10.11124/JBISRIR-D-19-00407           PMID:  https://pubmed.ncbi.nlm.nih.gov/32833789/

 

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