ASSESS
Identify each component of the PICO pneumonic:
P = patient, problem, population
I = intervention
C = comparison
O = outcome
ASK
Identify and develop a well-articulated question about either patient care issues or research issues using the PICO Worksheet. Then determine the study question category as either diagnosis, therapy/prevention, prognosis, or etiology.
ACQUIRE
Gather appropriate EBM information that answers the PICO question and correlates to designated levels of evidence. Then locate an article that answers the PICO question by searching the following:
• EBM Reviews - ACP Journal Club
• EBM Reviews - Cochrane Central Register of Controlled Trials
• EBM Reviews - Cochrane Database of Systematic Reviews
• NLM PubMed's Clinical Queries
• NLM PubMed’s ComparativeEffectivenes